Economic and Environmental human rights have come sharply into focus in the 21st century, as inequity and ecological degradation continue to surge in liberal democracies committed to political freedoms, including freedom of expression and assembly. The twin problems of Covid-19 pandemic and climate change have seriously threatened the life, livelihood and sustainability of the human development process all over the world in recent times. Application of the lens of entropy helps us to address the challenges — and explore the remedies — to abetting the progress of economic and environmental human rights. These problems when situated in the entropy perspective of  economic processes  point to the ecological links of these phenomena and to the critical issues of challenge posed by biodiversity loss and heating of the earth causing extreme  health related or related climate related events. This talk gives an overview of  these interrelated interdisciplinary issues concerning such events and shows how the rise of entropy as induced by the processes of economic growth lead to scarcities  of resources and income which threaten to raise in turn the social disorder or social entropy as well. The policy issues that emerge from such analyses are required to address economic,  social and  environmental aspects of sustainability of development from such a holistic scientific perspective. The paper concludes by pointing out how the  short and long run policy issues would   warrant revisiting some of the human rights issues in the background of such an entropy perspective.